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Ionically Imprinting-Based Copper (Ⅱ) Label-Free Detection for Preventing Hearing Loss Article
Huan Wang, Hui Zhang, Xiaoli Zhang, Hong Chen, Ling Lu, Renjie Chai
《工程(英文)》 doi: 10.1016/j.eng.2023.09.001
Copper is a microelement with important physiological functions in the body. However, the excess copper ion (Cu2+) may cause severe health problems, such as hair cell apoptosis and the resultant hearing loss. Therefore, the assay of Cu2+ is important. We integrate ionic imprinting technology (IIT) and structurally colored hydrogel beads to prepare chitosan-based ionically imprinted hydrogel beads (IIHBs) as a low-cost and high-specificity platform for Cu2+ detection. The IIHBs have a macroporous microstructure, uniform size, vivid structural color, and magnetic responsiveness. When incubated in solution, IIHBs recognize Cu2+ and exhibit a reflective peak change, thereby achieving label-free detection. In addition, benefiting from the IIT, the IIHBs display good specificity and selectivity and have an imprinting factor of 19.14 at 100 lmol∙L–1. These features indicated that the developed IIHBs are promising candidates for Cu2+ detection, particularly for the prevention of hearing loss.
关键词: Structural color Microfluidics Ionic imprinting Label-free detection Hearing loss
Digital microfluidics: A promising technique for biochemical applications
He WANG, Liguo CHEN, Lining SUN
《机械工程前沿(英文)》 2017年 第12卷 第4期 页码 510-525 doi: 10.1007/s11465-017-0460-z
Digital microfluidics (DMF) is a versatile microfluidics technology that has significant application potential in the areas of automation and miniaturization. In DMF, discrete droplets containing samples and reagents are controlled to implement a series of operations via electrowetting-on-dielectric. This process works by applying electrical potentials to an array of electrodes coated with a hydrophobic dielectric layer. Unlike microchannels, DMF facilitates precise control over multiple reaction processes without using complex pump, microvalve, and tubing networks. DMF also presents other distinct features, such as portability, less sample consumption, shorter chemical reaction time, flexibility, and easier combination with other technology types. Due to its unique advantages, DMF has been applied to a broad range of fields (e.g., chemistry, biology, medicine, and environment). This study reviews the basic principles of droplet actuation, configuration design, and fabrication of the DMF device, as well as discusses the latest progress in DMF from the biochemistry perspective.
关键词: digital microfluidics electrowetting on dielectric discrete droplet biochemistry
《化学科学与工程前沿(英文)》 页码 1643-1650 doi: 10.1007/s11705-022-2201-z
关键词: microcapsule emulsion microfluidics selective permeation stimuli-triggered release
Extractive desulfurization of model fuels with a nitrogen-containing heterocyclic ionic liquid
《化学科学与工程前沿(英文)》 2022年 第16卷 第12期 页码 1735-1742 doi: 10.1007/s11705-022-2167-x
关键词: extractive desulfurization nitrogen-containing heterocyclic ionic liquid reduced density gradient analysis desulfurization selectivity
Regularly channeled MXene membranes for ionic and molecular separation
Jingchong Liu, Nü Wang
《化学科学与工程前沿(英文)》 2021年 第15卷 第3期 页码 591-594 doi: 10.1007/s11705-020-1966-1
Fabrication of ionic polymer-metal composites (IPMCs) and robot design
Hanmin PENG, Qingjun Ding, Huafeng LI
《机械工程前沿(英文)》 2009年 第4卷 第3期 页码 332-338 doi: 10.1007/s11465-009-0046-5
关键词: ionic polymer-metal composites (IPMCs) artificial muscles actuator bionic robot platinum-plated
Systematic screening procedure and innovative energy-saving design for ionic liquid-based extractive
《化学科学与工程前沿(英文)》 2023年 第17卷 第1期 页码 34-45 doi: 10.1007/s11705-022-2234-3
关键词: ionic liquid entrainer screening feasibility analysis extractive distillation
Latest advances in ionic liquids promoted synthesis and application of advanced biomass materials
《化学科学与工程前沿(英文)》 2023年 第17卷 第7期 页码 798-816 doi: 10.1007/s11705-023-2316-x
关键词: biomass materials functional materials ionic liquids synthesis structure-property relationship
Selective removal of Cu(II) from contaminated water using molecularly imprinted polymer
QI Jingyao, LI Xin, LI Ying, ZHU Jianhua, QIANG Liangsheng
《化学科学与工程前沿(英文)》 2008年 第2卷 第1期 页码 109-114 doi: 10.1007/s11705-008-0019-y
关键词: synthetic divinylbenzene noncovalent imprinting imprinting technique temperature
Oxidative desulfurization of fuels using ionic liquids: A review? ?
Hua Zhao,Gary A. Baker
《化学科学与工程前沿(英文)》 2015年 第9卷 第3期 页码 262-279 doi: 10.1007/s11705-015-1528-0
关键词: oxidative desulfurization ionic liquids extraction fuels petroleum polyoxometalates
Rui YAO, Hua WANG, Jinyu HAN
《化学科学与工程前沿(英文)》 2012年 第6卷 第3期 页码 239-245 doi: 10.1007/s11705-012-1297-y
关键词: ionic liquid PEG-supported ionic liquid carbon dioxide propylene carbonate
Polymeric ionic liquid—assisted polymerization for soluble polyaniline nanofibers
Jie Liu, Jiahao Shen, Jingjing Wang, Yuan Liang, Routeng Wu, Wenwen Zhang, Delin Shi, Saixiang Shi, Yanping Wang, Yimin Wang, Yumin Xia
《化学科学与工程前沿(英文)》 2021年 第15卷 第1期 页码 118-126 doi: 10.1007/s11705-020-1916-y
Effects of ionic impurities on crystallization of cobalamin
Baoli SHAO, Hui CHEN, Shuang WANG, Haijun WANG, Shenmin XU,
《化学科学与工程前沿(英文)》 2010年 第4卷 第1期 页码 70-74 doi: 10.1007/s11705-009-0293-3
医用增材制造领域中的微流控技术 Review
王洁, 邵长敏, 王月桐, 孙凌云, 赵远锦
《工程(英文)》 2020年 第6卷 第11期 页码 1244-1257 doi: 10.1016/j.eng.2020.10.001
增材制造是食品、制药、医学和机械加工等领域的一种重要生产技术。得益于增材制造快速、低成本和可定制化的加工特性,医学增材制造推动了医疗器械、医学假体和临床移植物等领域的发展。在此背景下,高通量以及结构和组分把控精准等优势使微流控技术在医用增材制造领域显露头角,且已被应用于药物开发、组织工程和器官芯片的构建。本文综述了近年来微流控技术在医用增材制造领域的研究进展。首先,针对不同结构的液滴和纤维模板的构建,评估了基于微流控技术的医用增材制造的独特优势;其次,介绍了微流控技术在细胞定向、三维细胞培养、体外组织构建和细胞疗法方向的应用现状;最后,讨论了基于微流控技术的医用增材制造面临的挑战及其发展前景。
LIU Yaochi, XU Wei, XU Weijian, LIU Hanmao, ZHANG Xiaowen
《化学科学与工程前沿(英文)》 2007年 第1卷 第4期 页码 327-331 doi: 10.1007/s11705-007-0059-8
关键词: saturation molecular imprinting imprinting technology adaptability commercial
标题 作者 时间 类型 操作
Ionically Imprinting-Based Copper (Ⅱ) Label-Free Detection for Preventing Hearing Loss
Huan Wang, Hui Zhang, Xiaoli Zhang, Hong Chen, Ling Lu, Renjie Chai
期刊论文
Digital microfluidics: A promising technique for biochemical applications
He WANG, Liguo CHEN, Lining SUN
期刊论文
Porous ultrathin-shell microcapsules designed by microfluidics for selective permeation and stimuli-triggered
期刊论文
Fabrication of ionic polymer-metal composites (IPMCs) and robot design
Hanmin PENG, Qingjun Ding, Huafeng LI
期刊论文
Systematic screening procedure and innovative energy-saving design for ionic liquid-based extractive
期刊论文
Latest advances in ionic liquids promoted synthesis and application of advanced biomass materials
期刊论文
Selective removal of Cu(II) from contaminated water using molecularly imprinted polymer
QI Jingyao, LI Xin, LI Ying, ZHU Jianhua, QIANG Liangsheng
期刊论文
Polyethylene glycol-supported ionic liquid as a highly efficient catalyst for the synthesis of propylene
Rui YAO, Hua WANG, Jinyu HAN
期刊论文
Polymeric ionic liquid—assisted polymerization for soluble polyaniline nanofibers
Jie Liu, Jiahao Shen, Jingjing Wang, Yuan Liang, Routeng Wu, Wenwen Zhang, Delin Shi, Saixiang Shi, Yanping Wang, Yimin Wang, Yumin Xia
期刊论文
Effects of ionic impurities on crystallization of cobalamin
Baoli SHAO, Hui CHEN, Shuang WANG, Haijun WANG, Shenmin XU,
期刊论文